Development and Characterization of Thermal Water Gel Comprising Helichrysum italicum Essential Oil-Loaded Chitosan Nanoparticles for Skin Care

نویسندگان

چکیده

Helichrysum italicum essential oil (H. EO) is recognized for its anti-inflammatory, antimicrobial and wound-healing properties. The main goal of the present work was development characterization a gel formulation comprising H. EO loaded in chitosan nanoparticles (NPs) dermatological applications. EO-loaded NPs presented hydrodynamic diameter PdI about 300 nm 0.28, respectively, surface charge +19 mV. were prepared by means ionic gelation then incorporated into thermal water formulation. organoleptic physicochemical properties developed studied. remained stable under accelerated test conditions, maintaining pH, viscosity In addition, spreadability suitable topical application. Finally, performance application evaluated on skin volunteers using non-invasive methods, particularly, biometric evaluation. These assays showed that water-based with can improve hydration maintain healthy demonstrating putative role distinct

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ژورنال

عنوان ژورنال: Cosmetics

سال: 2023

ISSN: ['2079-9284']

DOI: https://doi.org/10.3390/cosmetics10010008